diff --git a/ci/test/00_setup_env_mac_native_arm64.sh b/ci/test/00_setup_env_mac_native_arm64.sh
index 1a7be56d5b..ade2d2787c 100755
--- a/ci/test/00_setup_env_mac_native_arm64.sh
+++ b/ci/test/00_setup_env_mac_native_arm64.sh
@@ -7,7 +7,9 @@
 export LC_ALL=C.UTF-8
 
 export HOST=arm64-apple-darwin
-export PIP_PACKAGES="zmq"
+# Homebrew's python@3.12 is marked as externally managed (PEP 668).
+# Therefore, `--break-system-packages` is needed.
+export PIP_PACKAGES="--break-system-packages zmq"
 export GOAL="install"
 # ELEMENTS: add -fno-stack-check to work around clang bug on macos
 export BITCOIN_CONFIG="--with-gui --with-miniupnpc --with-natpmp --enable-reduce-exports CXXFLAGS=-fno-stack-check"