diff --git a/doc/release-notes.md b/doc/release-notes.md
index 61c65d5a3e..01ef3610c9 100644
--- a/doc/release-notes.md
+++ b/doc/release-notes.md
@@ -108,6 +108,9 @@ RPC
 Tests
 -----
 
+- For the `regtest` network the BIP 66 (DERSIG) activation height was changed
+  from 1251 to 102. (#22632)
+
 Credits
 =======
 
diff --git a/src/chainparams.cpp b/src/chainparams.cpp
index 15b563a76f..0bf2956584 100644
--- a/src/chainparams.cpp
+++ b/src/chainparams.cpp
@@ -569,7 +569,7 @@ public:
         consensus.BIP34Height = 2; // BIP34 activated on regtest (Block at height 1 not enforced for testing purposes)
         consensus.BIP34Hash = uint256();
         consensus.BIP65Height = 1351; // BIP65 activated on regtest (Used in functional tests)
-        consensus.BIP66Height = 1251; // BIP66 activated on regtest (Used in functional tests)
+        consensus.BIP66Height = 102; // BIP66 activated on regtest (Block at height 101 and earlier not enforced for testing purposes)
         consensus.CSVHeight = 432; // CSV activated on regtest (Used in rpc activation tests)
         consensus.SegwitHeight = 0; // SEGWIT is always activated on regtest unless overridden
         consensus.MinBIP9WarningHeight = 0;
diff --git a/test/bitcoin_functional/functional/test_framework/util.py b/test/bitcoin_functional/functional/test_framework/util.py
index cb83ec20de..4f4b325f75 100644
--- a/test/bitcoin_functional/functional/test_framework/util.py
+++ b/test/bitcoin_functional/functional/test_framework/util.py
@@ -315,7 +315,7 @@ def initialize_datadir(dirname, n):
         f.write("walletrbf=0\n") # Default is 1 in Elements
         f.write("con_bip34height=100000000\n")
         f.write("con_bip65height=1351\n")
-        f.write("con_bip66height=1251\n")
+        f.write("con_bip66height=102\n")
         f.write("con_genesis_style=bitcoin\n")
         f.write("con_csv_deploy_start=0\n") # Default is -1 (always active)
         f.write("blindedaddresses=0\n")
diff --git a/test/functional/feature_dersig.py b/test/functional/feature_dersig.py
index eb027c554a..5dd6cb6cb2 100755
--- a/test/functional/feature_dersig.py
+++ b/test/functional/feature_dersig.py
@@ -4,10 +4,11 @@
 # file COPYING or http://www.opensource.org/licenses/mit-license.php.
 """Test BIP66 (DER SIG).
 
-Test that the DERSIG soft-fork activates at (regtest) height 1251.
+Test the DERSIG soft-fork activation on regtest.
 """
 
 from test_framework.blocktools import (
+    DERSIG_HEIGHT,
     create_block,
     create_coinbase,
 )
@@ -23,8 +24,6 @@ from test_framework.wallet import (
     MiniWalletMode,
 )
 
-DERSIG_HEIGHT = 1251
-
 
 # A canonical signature consists of:
 # <30> <total len> <02> <len R> <R> <02> <len S> <S> <hashtype>
@@ -90,8 +89,10 @@ class BIP66Test(BitcoinTestFramework):
         block.rehash()
         block.solve()
 
+        assert_equal(self.nodes[0].getblockcount(), DERSIG_HEIGHT - 2)
         self.test_dersig_info(is_active=False)  # Not active as of current tip and next block does not need to obey rules
         peer.send_and_ping(msg_block(block))
+        assert_equal(self.nodes[0].getblockcount(), DERSIG_HEIGHT - 1)
         self.test_dersig_info(is_active=True)  # Not active as of current tip, but next block must obey rules
         assert_equal(self.nodes[0].getbestblockhash(), block.hash)
 
diff --git a/test/functional/rpc_blockchain.py b/test/functional/rpc_blockchain.py
index 727bed4881..93c4d7e20d 100755
--- a/test/functional/rpc_blockchain.py
+++ b/test/functional/rpc_blockchain.py
@@ -28,6 +28,7 @@ import subprocess
 
 from test_framework.address import ADDRESS_BCRT1_P2WSH_OP_TRUE
 from test_framework.blocktools import (
+    DERSIG_HEIGHT,
     create_block,
     create_coinbase,
     TIME_GENESIS_BLOCK,
@@ -140,8 +141,8 @@ class BlockchainTest(BitcoinTestFramework):
         assert_greater_than(res['size_on_disk'], 0)
 
         assert_equal(res['softforks'], {
-            'bip34': {'type': 'buried', 'active': False, 'height': 500},
-            'bip66': {'type': 'buried', 'active': False, 'height': 1251},
+            'bip34': {'type': 'buried', 'active': True, 'height': 2},
+            'bip66': {'type': 'buried', 'active': True, 'height': DERSIG_HEIGHT},
             'bip65': {'type': 'buried', 'active': False, 'height': 1351},
             'csv': {'type': 'buried', 'active': False, 'height': 432},
             'segwit': {'type': 'buried', 'active': True, 'height': 0},
diff --git a/test/functional/test_framework/blocktools.py b/test/functional/test_framework/blocktools.py
index f02b65a126..90795e2df6 100644
--- a/test/functional/test_framework/blocktools.py
+++ b/test/functional/test_framework/blocktools.py
@@ -56,6 +56,7 @@ TIME_GENESIS_BLOCK = 1296688602
 COINBASE_MATURITY = 100
 
 # Soft-fork activation heights
+DERSIG_HEIGHT = 102  # BIP 66
 CLTV_HEIGHT = 1351
 CSV_ACTIVATION_HEIGHT = 432
 
diff --git a/test/functional/test_framework/util.py b/test/functional/test_framework/util.py
index 0dba605fc0..1fe52d4324 100644
--- a/test/functional/test_framework/util.py
+++ b/test/functional/test_framework/util.py
@@ -391,9 +391,9 @@ def write_config(config_path, *, n, chain, extra_config="", disable_autoconnect=
         f.write("con_connect_genesis_outputs=0\n")
         f.write("anyonecanspendaremine=0\n")
         f.write("walletrbf=0\n") # Default is 1 in Elements
-        f.write("con_bip34height=500\n")
+        f.write("con_bip34height=2\n")
         f.write("con_bip65height=1351\n")
-        f.write("con_bip66height=1251\n")
+        f.write("con_bip66height=102\n")
         f.write("blindedaddresses=0\n") # Set to minimize broken tests in favor of custom
         f.write("evbparams=dynafed:"+str(2**31)+":::\n") # Never starts unless overridden
         f.write("minrelaytxfee=0.00001\n")